Abstract: The article presents the results of comparative studies to study the effect of harvesting time on productivity and fodder benefits of mixed crops in the forest-steppe zone of Cisbaikalia. For cultivation in mixed crops, zoned varieties of oats, field peas (pelush) and vetch were used. It was revealed that jointly grown cereals and legumes, in all variants of the experiment, provided the yield of green mass higher than single-species sowing of oats. The most promising option was established, which gave the greatest increase in yield - 2.4 and 1.8 t / ha, respectively, in the first and second mowing of grass stand. The fodder productivity of mixed crops depended on the type of leguminous plants, their biological characteristics, seeding rates and harvesting periods. Early harvesting of herbs contributed to a higher supply of raw and digestible protein. The highest content of crude protein - 179.5 g and digestible - 131.2 g per 1 c.u. provided two-component oat and pelush sowing in a component ratio of 70:60%. When harvesting the grass stand at a later date, the protein content decreased in all variants of the experiment. The highest collection of feed units, due to the high content of dry matter in the vegetative mass, was determined in the single-species sowing of oats. In mixed crops, in terms of the yield of fodder units, in the first mowing, two-component oat-vetch crops and threecomponent cenosis were dominant, while in the second, on the contrary, oat-pelush crops were predominant. It was found that all cultivated crops, harvested at a later date, provided a higher yield of crude and digestible protein

Keywords: oats, pelush, vetch, mixed sowing, legumes, green mass, productivity, nutritional value.

Abstract: The search for antagonistically active cultures of bacilli to fungal and bacterial pathogens of sugar beet lump rot was carried out. Filamentous fungi are represented by such genera as Aspergillus spp., Fusarium spp., Penicillium spp., Alternaria spp., Mucor spp. and others. The study involved 44 cultures of bacilli to 10 microscopic fungi, 5 bacteria, 5 yeast and 5 enterobacteria. For further work, 14 working bacilli were selected, which have good antagonistic properties. Investigated 54 lactobacilli to the same pathogens - fungi, yeast, endobacteria, but they gave weak indicators of antagonism. Physiological and biochemical properties of 14 active strains for viability and genotyping were carried out. As a result of screening antagonistically active bacilli, it was found that the main components for inclusion in the preparation are bacterial cultures: 6B, 17B, 23B, 29B, 32B, 36B, 14B, 39B, 40B, 41B, C 154. They act on a wide range of microorganisms, have high rates of antagonistic activity and suppress up to 6 - 7 pathogens of fungal, bacterial and yeast nature.To create a complex preparation against the pathogens of clump rot, several strains are needed that can suppress the activity of phytopathogenic fungi, bacteria, and yeast as much as possible. For this purpose, an assessment of the biocompatibility of 14 antagonistically active cultures of bacilli was carried out and a domestic biological product was created on the basis of strains isolated from substrates of local origin to protect sugar beets from lagging rot during storage, which is an urgent problem not only in Kazakhstan, but also in other beet-growing countries.

Keywords: sugar beet, knot rot, storage, microorganisms, bacteria, lactobacilli, microscopic fungi, yeast, enterobacteriaceae, antagonistic activity, biocompatibility.

Abstract: Rye has a rich mineral composition and products of its processing are actively used in the national economy and in feeding animals. In this work, a comparative analysis of the trace element composition was carried out using the example of rye grown in the Baikal region, for samples with and without mineral fertilization with nitrogen (urea). The following parameters were selected for the study: potassium, phosphorus and calcium, as well as sugar colloids (starch, pentosans) and ash content. Experimental measurements were carried out using a certified infrared analyzer ―InfraLUM® FT-12‖ for two investigated rye samples (―control‖ and ―carbamide‖). On average, with an increase in moisture from 10% to 20%, the starch level increased by 10% for the sample with feeding and by 13% for the second sample. At the same time, in the sample with feeding, the amount of starch is on average 3% higher, the differences are most noticeable at a moisture content of less than 15%. The regression equations have the form y=1,183x+44,657 (for a sample of the ―urea‖ variety) and y=1,676x+36,548 (for a sample without mineral feeding). Here y - moisture,%, x - starch level,%.The accuracy of the approximation is 0,98. Pentosans, which are sugar colloids, have a direct effect on the characteristics of rye dough, swelling easily in an aqueous medium, they form a viscous solution that plays the role of a binder fraction. There is an interdependence with a high correlation coefficient of the starch and ash content on the moisture content of the studied samples of the grain crop with and without mineral feeding. The amount of macronutrients (phosphorus, potassium, calcium) does not actually change with a change in grain moisture (variations are 0.15-0.25%).

Keywords: rye, macroelements, ash content, starch, potassium, phosphorus, calcium, pentosans, moisture content, urea, sugar colloids

Abstract: As a result of the studies carried out to assess the antifungal and growth-stimulating properties of some biological products based on natural components, widely used and planned for use in greenhouse vegetable growing, it was shown that to reduce the infection with phytopathogens of vegetative cucumber plants, to stimulate the growth of microplants, a liquid spore suspension of microscopic fungus Trichoderma atrobrunneum VKPM F-1434 from the educational collection of the Department of Biotechnology, Orlov State Agrarian University. This study shows for the first time that a new agent based on the fungus of the genus Trichoderma atrobrunneum VKPM F-1434, which contains a spore suspension of the fungus and a sorbent with an inhibitor of cell metabolism, has a complex of biological properties: pronounced growth-stimulating properties in relation to cucumber microplants, the ability to inhibit growth phytopathogenic fungi of the genus Fusarium, stimulate the growth of cucumber seedlings due to auxin- and gibberellin-like activity. Liquid spore suspension Trichoderma atrobrunneum VKPM F-1434 is a strong antagonist against fungi of the genus Fusarium; it stimulated plant growth both by cell division and cell expansion. It has auxin and gibberellinlike effects. Biopreparations ―Sporobacterin‖, ―Fitolavin‖, ―Elixir of the Harvest‖, as well as a new agent based on the Trichoderma atrobrunneum strain VKPM F-1434, effectively stimulate germination energy, germination of cucumber seeds, as well as the growth and development of seedlings. The efficiency of their use in greenhouse vegetable growing to increase plant productivity and obtain environmentally friendly products in organic farming has been confirmed

Keywords: phytopathogens, biological products, vegetable crops, fusarium, antifungal properties, growth-stimulating properties.

Abstract: The study was carried out in the collection of introduced woody plants of the Polar-Alpine Botanical Garden-Institute. The material was phenological observations of 219 samples of introduced woody plants in Kirovsk in 2000-2019. The peculiarities of flowering of woody deciduous plants are determined, consisting in the regularity, timing and duration of flowering, the duration of the prefloral period. A flowering calendar was compiled for 203 accessions belonging to 134 taxa of 29 genera of 14 families. In the investigated flowering plants, the growing season begins within 19 days (from May 23 to June 11). In most samples, the growing season begins at a later date from May 30. Depending on the regularity of flowering, the plants are classified into three groups: non-flowering, flowering irregularly, flowering annually. 85 samples of deciduous introduced species were assigned to the irregular flowering group. The irregularity of flowering is associated with the old age of plants, with the inconsistency of environmental conditions with seasonal rhythms of development, with the biological characteristics of the species. The blooming group includes 118 samples. This group includes both middle-aged and young plants and old-aged plants. More than 90% of the examined samples of introduced deciduous trees and shrubs are in bloom. The massive beginning of flowering of trees and shrubs is observed in July. Plants are classified into two groups according to the length of the prefloral period: short (up to 30 days) and medium (31-60 days). A short prefloral period is typical for plants that bloom in June. Plants blooming in July and August have a short to medium prefloral period.

Keywords: : introduction, trees and shrubs, flowering, prefloral period, Polar region, PolarAlpine Botanical Garden-Institute

Abstract: The article presents the results of using different types of lilacs in agrocenoses of a park landscape for gardening Krasnoyarsk. The creation of a favorable urban environment for residents of industrial centers is an urgent task. When using plants, the agro-ecological conditions of their growth should be taken into account. Lilac (Syringa) is widely used in landscaping Siberian cities and is a representative of essential oil plants. Scientific novelty is expressed in the fact that as a result of geobotanical research, the possibility of using cultural species of lilacs adapted to the environmental conditions of the city of Krasnoyarsk has been determined. Park-type agrocenoses are the basis of park landscapes, which is defined as a structural component of the garden-park landscape. The technology of plant selection, in combination with agricultural techniques and methods of soil cultivation, contributes to their high productivity. In the phytocompositions of the park type of the city of Krasnoyarsk, lilacs are usually used, represented by common lilac (Syringa vulgaris L.) and Hungarian lilac (Syringa josikaea Jacq.). It is recommended to use the following types of lilacs more often: Wolf lilac (Syringa wolfii C.K.Schneid.), Amur lilac (Syringa amurensis Rupr.), Hairy, hairy (Syringa villosa Vahl.), Adapted to growing in Siberian conditions

Keywords: Krasnoyarsk, urban environment, landscaping, park-type agrocenosis, lilacs, types of lilacs, phytocompositions.

Abstract: The article presents data on the study in field experimental experiments of a comparative assessment of the productivity of forage crops and crop rotations in general. Field experiments were carried out on the experimental field of the Irkutsk Scientific Research Institute of Agriculture (Pivovarikha, Irkutsk region). The soil of the site is gray forest. Three fodder fivefield crop rotations were established. Crop rotations are deployed in time and space. Perennial leguminous plants as predecessors had a positive effect on crop productivity in forage crop rotations without the use of mineral fertilizers. Thus, the productivity of crop rotations with perennial legumes (sand sainfoin) exceeds the control variant by 16.6%. The maximum productivity of the silage crop (maize) was achieved in crop rotations with sainfoin and amounted to 2.1-2.2 t / ha KU. In the link of crop rotation, peas-oats cultivated for grain, this indicator increases by 12% in comparison with the control. The collection of exchangeable energy of forage crops on average for the control crop rotation for the years of research was 23.3 GJ / ha, 26.0-27.2 GJ / ha in crop rotations with sainfoin fields. Thus, the content of exchangeable energy in the control variant in barley was 18.6 GJ / ha, and in crop rotations with perennials it increased by 26.3%, in maize for silage this indicator increased by 10.2% compared to the control, and in the pea-oats link by 3.1%. The energy efficiency factor is 87.5% ahead of control. Based on the data obtained, the most productive crop rotations were determined with sand sainfoin (2-4 fields), characterized by high productivity, provision of 1 fodder unit with digestible protein up to 99 g, a high level of net income and profitability 140.6 - 159.8%. leguminous grasses, optimal conditions are formed for the growth and development of agricultural crops, which contributes to obtaining high and stable yields without expensive mineral fertilizers and obtaining a good forage base

Keywords: crop rotations, perennial legumes, productivity, protein, metabolic energy.

Abstract: The basis of the herbage of perennial grasses is the root system and seeds. The study of the influence of the seeding rate and the method of sowing on the development of the root system of awnless rump is relevant for the region. As an object of research, we took a promising variety of awnless rump ―Ammachaan‖, which is grown in the conditions of the 2nd above-floodplain terrace in the middle reaches of the Lena River. The subject of this research is to study the influence of different sowing methods on the growth and development of the root system of rump plants. The purpose of the work is to assess the impact of different seeding rates and sowing method on the root system of the rump. In experimental studies, the method of the field experiment by B.A. Dospekhov, in assessing biometric indicators - the methodology of the AIPand ARIF named after V.R. Williams. Statistical data processing was carried out using the SNEDECOR program and using the Microsoft Office Excel 2007 software package. The research results showed that when creating an optimal herbage for the testes of the awnless rump variety Ammachan, it is necessary to sow seeds according to the sowing method 30x30 cm. This method ensures the amicable formation of the aboveground mass up to 4195 g/m2, root mass at the level of 841 g/m2. These indicators are reliable at the 95% significance level. Root productivity was maximally noted at the level of 5.76 in the variant with the sowing method of 15x15 cm, which is 1.3 times higher than the control variant with the continuous sowing method. It has been established that the feeding area according to sowing methods with dimensions of 30x30 cm and 15x15 cm can be considered as respectable.

Keywords: awnless rump, root system, root productivity, sowing method, aboveground mass

Abstract: The quality of resources of natural systems and the dynamics of their state is an important factor in the well-being of the population of rural areas of Siberia. At the ―Menza‖ station, located on the territory of the Khentei-Chikoisky Upland (Krasnochikoysky District of the Trans-Baikal Territory), long-term studies of economically important plant populations (mainlycedar (Pinus sibirica Du Tour) and animal squirrels (Sciurus vulgaris L. , 1758) and sable (Martes zibellina L., 1758) .The dynamics of the yield of stone pine forests, as well as fluctuations in the number of animal populations, to a large extent depend on the weather conditions directly in the places of their location. To assess resources, quantitative and qualitative forecast of their reproduction, both As a rule, only the data of economic statistics are not enough. The paper proposes a solution method using the tools developed by the authors for the ecosystems of the cedar forests of Transbaikalia. The main problems arising in the retrospective analysis of observations of the state and processes in the ecosystems of the southern mountain forests of Transbaikalia are considered. of weather data in the ecosystem location is the main factor that complicates the interpretation of previously accumulated observational data and the determination of the nature of the influence of weather conditions on the processes and state of the ecosystem. The authors point out the fundamental possibility of obtaining meteorological data at the location of the observed ecosystem by calculation methods in retrospect up to several decades, based on the meteorological data archives from the meteorological stations of the Hydrometeorological Center of Russia. A description of the device developed by the authors is given, the main purpose of which is to collect data necessary for retrospective calculations of weather conditions in the location of the observed ecosystem

Keywords: Hentey-Chikoyskoye highlands, cedar forests, long-term studies, meteorological data, artificial neural networks, electrophysiological parameters.

Abstract: Data on the presence of different reptile species in the Eastern Transbaikalia for 15 years (2005 - 2020) are generalized. Two species of lizards have been recorded: the Mongolian racerunner – Eremias argus Peters, 1869 and the viviparous lizard – Zootoca vivipara Jacquin, 1787 and three species of snakes: the dione ratsnake - Elaphe dione Pallas, 1773, the halys pit viper – Gloydius halys Pallas, 1776 and the Ussuri pit viper – Gloydius ussuriensis Emelianov, 1929. The average index of the Mongolian racerunner was 3.0 ± 1.0 individuals / 100 cylinderdays, and the maximum values were recorded in 2013 and 2018. Visually, it is a view in the cold wormwood-onion-feather grass steppe, which occupies gentle elevated areas between the Torey lakes. A viviparous lizard was recorded in the middle reaches of the river Nikishikha (tributary of the Ingoda). The most widespread and numerous species of snakes is the dione ratsnake, therefore it is recommended to exclude this species from the Red Book of the Zabaikalsky krai. On the contrary, the viper requires purposeful study and protection, which has not been reliably registered for several decades. Both Sakhalin – Vipera sachalinensis Tsarevsky, 1916, and common viper – V. berus Linnaeus, 1758, can live in the region. Information about the finds in the region of the grass snake - Natrix natrix Linnaeus, 1758, which initially served as the basis for entering the species into the regional Red Book, is extremely doubtful. As for two more protected species - the Mongolian racerunner and the Ussuri pit viper, they are common in the corresponding habitats, although they are located in the Eastern Transbaikalia at the edge of their ranges

Keywords: snakes, lizards, Red Data Book, ranges, Eastern Transbaikalia

Abstract: The dynamics of the number of grouse birds inhabiting the territory of CJSC ―Ust-Ilimsk Zveropromkhoz‖ for 2015 - 2020 is considered. based on farm reports. The total area of CJSC ―Ust-Ilimsk Zveropromkhoz‖ is 2,251,669 ha. Forests occupy 88.8% (80% of the territory -coniferous forests) of the area of the district and stretch along both banks of the river. Angara. The species composition of birds is represented by the following species: common black grouse (Lyrurus tetrix L. 1758), common wood grouse (Tetrao urogallus L. 1758), hazel grouse (Tetrastes bonasia L., 1758). The number of grouse birds is constantly changing from year to year, it depends both on natural causes and on anthropogenic influences. Since 2015, the population density of the common wood grouse has steadily increased until 2018 (10.2 -17.8 ind./ha), and then in 2019 it sharply decreased - to 10 ind./1000 ha. The maximum indicators of the common black grouse for six years were observed in 2015 - 32.8 ind./1000 ha. In general, the number of wood grouse for 2016 - 2020 remained practically stable. At the same time, the maximum numbers were recorded (2015), when the maximum population density of hazel grouse is observed over the past 6 years - 47.8 individuals / 1000 ha. In 2019, the quantitative indicators of hazel grouse significantly decreased to 29.3 species / 1000 ha. The population density of black grouse living in the lands of CJSC ―Ust-Ilimskiy Zveropromkhoz‖ has tended to decrease over the past six years. One of the significant unfavorable factors affecting the number of grouse birds is extensive forest fires.

Keywords: common black grouse (Lyrurus tetrix, L.), common wood grouse (Tetrao urogallus, L.), hazel grouse (Tetrastes bonasia, L.)., Ust-Ilimsky fur industry, dynamics.

Abstract: One of the main tasks of forestry in Russia is to protect forests from harmful organisms. In this regard, the subsequent state of the forests depends on its effective solution. The sanitary state of the taiga massifs of the Irkutsk region is assessed on the basis of data from the state forest pathological monitoring carried out by ground and remote methods, as well as according to the results of forest pathological examinations. At the same time, the main reasons for the change in the sanitary state of the forests of the Irkutsk region include: fires, forest diseases and insect damage. Since the beginning of the fire hazardous season in 2018, 632 forest fires have been registered in the forests located on the lands of the forest fund of the Irkutsk region; the area covered by fires was 88 130.2 hectares, including the area covered with forest - 77 034.4 hectares. In addition, 128 forest fires with a total area of 225 061 ha were registered in the forest fire control zone, including the forested area of 207 173.9 ha. At the same time, forest pathological examinations and sanitary and recreational activities during the period under consideration covered an area of 28 142.54 hectares. This publication contains the results of the analysis of publicly available materials of forest pathological surveys, as well as personal field observations in the places of sanitary and recreational activities (SRA). Public control and monitoring of acts of forest pathology survey (FPS) in the Irkutsk region in the period from October 2018 to June 2019 was carried out with the support of the Altai-Sayan branch of WWF. Its results confirmed that there were foci of harmful organisms practically in all surveyed forest areas. SRA were assigned to prevent contamination of adjacent territories. In this regard, within the framework of public monitoring of SRA in the region, work was carried out to assess its quality.

Keywords: forest pathological examinations, clear sanitary cuttings, selective sanitary cuttings

Abstract: The article analyzes the population indicators of the mass species of non-atomic algae in Lake Baikal. For mass species, the number of which has repeatedly reached values of more than 100 thousand cells ∙ l-1are taken. During the studied period in the pelagic zone of Lake Baikal, 6 species of non-atomic algae were registered as massive ones: Gymnodinium baicalense(dinophytes), Rhodomonas pusilla (cryptophytes), Koliella longiseta and Monoraphidium pseudomirabile (green), Dinleоbryon sociale var. sociale and Chrysochromulina parva(golden). G. baicalense was found in samples from January to June; the maximum development of the species was observed during the ice period - in March - April. Rh. pusilla was found in samples throughout the year; the maximum development of the species was observed in the summer period (June - September). D. sociale var. sociale appeared in small quantities in phytoplankton in May - June (during the spring homothermy), the maximum development of the species was observed in August - September (summer period), starting from October its concentration sharply decreased and in November - December the species was found in small quantities. Ch. parva was found in samples throughout the year; the maximum development of the species was observed in the summer period (July - September). M. pseudomirabile was found in samples throughout the year; the maximum development of the species was observed in April under the ice, and also in July - August in summer. K. longiseta in samples throughout the year; the development of the species began under the ice (in February – March), the maximum development occurred under the ice in April, and during the period of spring homothermia in June; in summer and during the autumn homothermy, the species was found in very small quantities. All common species (with the exception of Rh. Pusilla) of nondatomal algae are characterized by sharp interannual fluctuations in abundance.

Keywords: phytoplankton, succession, species composition, abundance, biomass, Baikal.

Abstract: The studies were carried out to reveal the dependence of the size of the fruiting body of the mushroom Russula integra on the weight of its cap. A collection of material was carried out in the vicinity of the villages of Oyok and Nikolsk, Irkutsk District, Irkutsk Region, in a coniferous forest, in August 2020. 179 fruiting bodies were weighed with an accuracy of 0.1 g, the diameter of their caps was measured with an accuracy of 1 mm. The diameters of the caps varied from 20 to 144 mm, their weight varied from 0.5 to 59 g. The largest number of mushrooms falls on the middle classes in the range from 40 to 59 mm - 87 pcs. (48.6%). The calculated mean values for all classes demonstrate a direct dependence of the weight of the mushrooms on the size. The maximum increase in weight is observed in the first stages of development, from 20 to 39 mm it is 100%, from 40 to 59 mm - 51.7%. With further growth of the caps, the percentage of weight gain decreases. The correlation coefficient r ± mr = 0.78 ± 0.02 indicates a high relationship between the studied values. The larger the cap, the higher the weight of the whole russula fruit body. Regression analysis showed that an increase in the cap size by one mm increases the weight of the fruiting body of the fungus by 0.602 g. without the laborious operation of collecting and weighing them.

Keywords: mushrooms, Russula integra, correlation coefficient, cap size, fruit body weight

Abstract: Determination of the species composition, ecological assessment, places of occurrence and resource potential of useful plants of the Brassicaceae family of Irkutsk and Irkutsk region has been carried out. The list of useful plants was compiled based on the results of expeditionary work, herbarium material and literary sources. Wild plants of the family are represented by 61 species, of which 54 species, 29 genera, are useful, used in various spheres of economic activity. Medicinal plants - 52, melliferous - 37 species, including: Alyssum obovatum (C.A. Mey.) Turcz., Brassicacam pestris L, Camelinam icrocarpa Andrz., Cardam inepratensis L., create a base for beekeeping in the Irkutsk region. Food - 24 , forage - 22, the most important are Brassicanapus L, Brassicacam pestris L., Bunias orientalis L, Sinapis alba L, Sisymbrium loeselii L. Poisonous - 9, decorative - 14, technical 15 species. Ten types are used as cosmetics. The share of mesophytes is 50.0%, growing in conditions of moisture deficit 33.3%, preferring places of growth with high soil moisture content of 16.7%. Mesotrophs - 64.8%, oligotrophs -11.1%, eutrophs developing well on fertile soils 24.1%. In relation to light, almost all species, with the exception of Cardam inemacrophylla Willd., Are photophilous. For the procurement of raw materials, it is possible to recommend species that are widespread throughout the region: Capsella bursa-pastoris (L.) Medik., Descurainiasophia (L.) Webbex Prantl, Draba nemorosaL., in limited quantities: Arabis pendula L., Erysimum cheiranthoides L., Rorippa palustris (L.) Besser, Thlaspiar vense L.

Keywords: family Brassicaceae, useful plants, poisonous plants, food plants, medicinal plants, ornamental plants, industrial plants, melliferous plants

Abstract: For the cultivation of highly productive plantations, it is necessary to have a permanent forest seed base in order to obtain seeds of high hereditary and sowing properties. As our research has shown, there is an insufficient number of forest seed objects in the Irkutsk region. All available forest seed plantations are pine. This tree species is one of the main forest-forming species of the Irkutsk region. The author has developed a project for the creation of a clonal forest seed plantation (FSP) of Siberian larch (Larix sibirica Ledeb) of vegetative origin. To create clones of trees, cuttings from plus trees are harvested, and grafted onto young rootstocks, specially rotated for this. A forest plot of a total test plantation with an area of 5.0 hectares was selected. A preliminary survey of the area was carried out for the presence of infestation by pests and diseases. The forest seed plantation belongs to the first order, as it is represented by the offspring of 50 plus trees. The allotment of a rectangular section with a flat relief and the presence of access roads was made. Minus plantations, trees near 300 m from the area of the FSP were absent. Soil cultivation was carried out in accordance with the requirements for forest seed plantations. The placement of trees on the seed plantation is not dense, which will promote good crown formation and seed production in the given forest conditions. In just 60 years of operation of FSP larch, the total estimated volume of seed harvesting will be 4800.0 kg, i.e. 80.0 kg for the average design year of the fruiting period or 16.0 kg per 1 ha. The return on costs of our project is 129.9%. This means that the proceeds from the sale of the improved seeds cover the costs of their production and on top of that, there will be profits

Keywords: Siberian larch, forest seed plantation, scion, crown, phenology, payback, costs, fruiting, seeds.

Abstract: In humans, a disease with the appearance of angiomatous foci of the retina is called Hippel-Lindau and can lead to complete blindness. The article discusses a clinical case of corneal angiomatosis in a dog. The clinical manifestation of corneal angiomatosis in dogs looks like symmetrically located on the lateral and medial sides of the cornea, affecting the limbus zone, neovascularization foci with clear edges, 0.5-3 mm thick, completely epithelialized. The described foci do not disturb the animal in any way. Unlike humans, no retinal angiomatous foci were found in dogs. Cytological examination of the corneal vascular formation revealed multiple mesenchymal cells; anisocytosis and anisocariosis of cells of mesenchymal origin, there are inflammatory cells - macrophages, lymphocytes and single granulocytes. Histological examination - dystrophic changes in multilayer squamous non-keratinizing epithelium with areas of hyperpigmentation of the basal layer, in the underlying stroma of the sclerosis zone, edema, angiomatosis with swelling endothelium, with chronic inactive inflammation and gaping vessels. A variant of treatment of vasculoproliferative processes of the cornea in dogs with subconjunctival use of dexamethasone in prolonged form (dexafort) and topical application of 0.03% tacrolimus is proposed. Tacrolimus reduces T cell activation, T helper dependent B cell proliferation. Dexamethasone inhibits the release of inflammatory mediators and reduces thepermeability of the capillary wall, the anti-inflammatory effect of dexamethasone is associated with inhibition of the release of inflammatory mediators by eosinophils and mast cells and with a decrease in capillary permeability. Clinical improvement of the condition occurred within 7 days, after 1 month the cornea of the eyes became completely free of angiomatous foci. After 3 months of using tacrolimus, the cornea remained healthy

Keywords: dog, cornea, angiomatosis, vasculoproliferative processes